Lühiartikkel: PGF2α ja parenteraalselt manustatava tseftofuuri kasutamine poegimisjärgsete emakapõletike ravis lüpsilehmadel

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Date
2017Author
Jeremejeva, Julia
Orro, Toomas
Kask, Kalle
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Present study was designed to get additional knowledge
about treatment of postpartum (PP) clinical metritis (CM) and clinical
endometritis (CE), using combination of systemic antibiotics with
administration of prostaglandin F2α (PGF2α), to determine the optimal
time of treatment, to study effect of this treatment on clinical,
physiological and fertility parameters.
Late pregnant dairy cows with diagnosed CM and CE were divided to the
experimental and positive control groups and negative control groups were
composed of healthy cows. Measurements of body temperature, examination
of general health status and vaginal discharge, bacteriological and
cytological examinations, determination of plasma or milk progesterone,
measuring of acute phase proteins and data of fertility parameters were
used for evaluation of treatment success. Using of combination of systemic
administrations of ceftiofur with two injections of PGF2α at intervals of 8
h was compared with using of combination of intramuscular administration
of ceftiofur with flunixin. Treatment of CE using systemic administrations
of ceftiofur with two injections of PGF2α with an interval of 8
h in the early PP (5–10 day after calving) was compared with treatment in
the late PP (30–35 day PP). The findings of the present study indicate that
treatment of CM and CE using flunixin in addition to parenteral antibiotic
did not improve clinical cure, inflammatory parameters or elimination of
bacteria from the uterus. Regardless of more severe inflammation that was
detected in animals from the group treated by parenteral administration of
antibiotic with PGF2α they showed the same fertility parameters as
healthy animals. Results of this study suggests that treatment of CE in the
early PP period, using systemic administration of ceftiofur with two
injections of PGF2α at an interval of 8 h, could be more preferable to using
the same treatment in the late PP.
URI
http://hdl.handle.net/10492/3643http://agrt.emu.ee/pdf/2017_1_jeremejeva.pdf
http://dx.doi.org/10.15159/jas.17.04