The effect of monensin on the metabolism of transition dairy cow
| dc.contributor.advisor | Karis, Priit (juhendaja) | |
| dc.contributor.author | Lauronen, Päivi Hannele | |
| dc.date.accessioned | 2023-06-02T11:02:51Z | |
| dc.date.available | 2023-06-02T11:02:51Z | |
| dc.date.defensed | 2023-06-08 | |
| dc.date.issued | 2023 | |
| dc.description | Final Thesis Curriculum in Veterinary Medicine | eng |
| dc.description.abstract | The aim of this final thesis was to find out if monensin influences metabolites non-esterified fatty acids (NEFA), β-hydroxybutyrate (BHB), aspartate aminotransferase (AST) and glucose dynamics during transition period. Research was done on a commercial Estonian dairy farm. There were 206 cows in the experiment. Randomly selected cows belonged either Controlgroup (no monensin) or cows were administered continuous release monensin capsule about three weeks before expected parturition (Kex-group). Blood samples were taken from both groups from the day of enrolment till 6 weeks after parturition. Due to the limitations of the testing software, there was 81 randomly selected cows in both groups. Blood samples were analyzed for BHB, NEFA, AST and glucose values. Cow was considered to be hyperketonemic if theBHB concentrationwas ≥1.2 mmol/L at least once during 6weeks after parturition. Cows with NEFA concentration ≥0.7 mmol/L at least once during 6 weeks after parturition, were considered having elevated concentrations of NEFA. Results show that monensin did lower the BHB and NEFA values but did not have significant effect on AST and glucose. In addition, monensin lowered the incidence of ketosis as well as the incidence of elevated NEFA. | eng |
| dc.description.abstract | Käesoleva lõputöö eesmärk oli välja selgitada monensiini mõju metaboliitide esterdamata rasvhappeid (NEFA), β-hüdroksübutüraadi (BHB), aspartaataminotransferaasi (AST) ja glükoosi konvtratsioonile üleminekuperioodil. Uuringud tehti Eesti tootmisfarmis. Katses osales 206 lehma. Juhuslikult jagati lehmad kas kontrollrühma (ilma monensiinita) või katserühma. Katserühma lehmadele manustati lehmadele umbes kolm nädalat enne eeldatavat poegimist monensiini pidevalt vabastav vatsabool. Vereproovid võeti mõlemas rühma loomadelt alates katsesse võtmisest kuni kuuenda poegimisjärgse nädalani. Statistilise analüüsi programmi piiratuse tõttu võrdsustati rühma loomade arv 81 juhuslikult valitud lehmani. Vereproovideste analüüsiti BHB, NEFA, AST ja glükoosi väärtusted. Lehma loeti ketoosis olevaks kui BHB kontsentratsioon oli ≥1,2 mmol/L vähemalt korra 6 nädala jooksul pärast poegimist. Lehmadel, kelle NEFA kontsentratsioon oli ≥0,7 mmol/L vähemalt üks kord 6 nädala jooksul pärast poegimist, loeti kõrge NEFA kontsentratsiooniga lehmaks. Tulemused näitavad, et monensiin alandas BHB ja NEFA väärtusi, kuid ei avaldanud olulist mõju AST-le ja glükoosile. Samuti vähendas monensiin ketoosi ja kõrge NEFA-ga loomade arvu. | est |
| dc.identifier.uri | http://hdl.handle.net/10492/8459 | |
| dc.publisher | Eesti Maaülikool | est |
| dc.rights | info:eu-repo/semantics/openAccess | eng |
| dc.subject | magistritööd | est |
| dc.subject | master thesis | eng |
| dc.subject | monensin | eng |
| dc.subject | ketosis | eng |
| dc.subject | β-hydroxybutyrate | eng |
| dc.subject | non-esterified fatty acids | eng |
| dc.title | The effect of monensin on the metabolism of transition dairy cow | eng |
| dc.title.alternative | Monensiini mõju piimalehma ainevahetusele üleminekuperioodil | est |
| dc.type | info:eu-repo/semantics/masterThesis | eng |
| rioxxterms.freetoread.startdate | 08.09.2023 |