Astelpaju töötlemise kõrvalsaaduste mõju hobuste insuliini regulatsioonile
Laen...
Kuupäev
2025
Kättesaadav alates
04.09.2025
Autorid
Ajakirja pealkiri
Ajakirja ISSN
Köite pealkiri
Kirjastaja
Eesti Maaülikool
Abstrakt
Astelpaju erinevad taimeosad on rikkad erinevate bioaktiivsete ainete ja toitainete poolest,
mille tõttu on taimel märkimisväärne meditsiiniline potentsiaal. Seda kinnitavad mitmed
inimeste ja loomadega läbiviidud uuringud. Palju kasulikke aineid sisaldavad ka
astelpajukasvatuse tootmisjäägid. Astelpaju efektiivsust insuliini düsregulatsiooni puhul on
täheldatud nii inimestel kui ka närilistel. Hobustel on insuliini düsregulatsiooni seostatud
endokriinhaiguste nagu hobuste metaboolse sündroomi ja hüpofüüsi vahesagara
talitlushäirega, süsteemse põletiku, füsioloogiliste tegurite ja vale söödavalikuga. Insuliini
düsregulatsioon võib hobustel esile kutsuda endokrinopaatilist laminiiti.
Töö eesmärgiks oli uurida astelpajukasvatuse tootmisjääkide kasutamise potentsiaali hobuste
metaboolse sündroomi ja insuliini düsregulatsiooni väljakujunemise ennetamises ja kontrolli
all hoidmises. Autorile teadaolevalt ei ole varasemalt hobustel vastavaid uuringuid tehtud.
Katse viidi läbi 34 hobusega, kellest 18 kuulusid katsegruppi ja 16 kontrollgruppi.
Katsegrupile söödeti kuue nädala jooksul astelpaju seemnetega marjapressijääki sisaldavaid
graanuleid ning kontrollgrupile vastavalt kanepiseemnete koortest valmistatud graanuleid.
Katse esimesel, 21. ja 42. päeval mõõdeti kõigi katses osalenud hobuste vereseerumi insuliini
kontsentratsiooni ja sooritati põhjalik kliiniline läbivaatus. Katseperioodi jooksul ei
toimunud katse- ega kontrollgrupi hobuste seerumi insuliini kontsentratsioonis statistiliselt
olulisi (p<0,05) muutusi. Siiski esines katsegrupis tendents selles suunas (p = 0,10).
Kinnitamaks astelpaju sisaldavate lisandsöötade mõju hobuste insuliini düsregulatsioonile on
vajalikud täiendavaid uuringuid.
Various parts of the sea buckthorn plant are rich in bioactive compounds and nutrients, giving the plant significant medicinal potential, as supported by multiple studies in humans and animals. Processing by-products from sea buckthorn cultivation also contain many beneficial components. The effectiveness of sea buckthorn in managing insulin dysregulation has been observed in humans and rodents. In horses, insulin dysregulation has been associated with endocrine disorders such as equine metabolic syndrome and pituitary pars intermedia dysfunction, as well as systemic inflammation, some physiological factors, and inappropriate diets. Insulin dysregulation in horses can cause the development of endocrinopathic laminitis. The aim of this study was to investigate the potential of sea buckthorn processing by-products in preventing and managing the development of insulin dysregulation and metabolic syndrome in horses. To the author’s knowledge, no similar studies have previously been conducted in horses. The study was conducted with 34 horses, 18 horses in the treatment group and 16 in the control group. For six weeks the treatment group received sea buckthorn pomace granules containing seeds and the control group received granules made from hemp seed hulls. On the first, 21st and 42nd day of the study blood serum insulin concentrations were measured and a thorough clinical evaluation was done in all horses. No statistically significant (p<0.05) changes in serum insulin concentration were found in the treatment or control group. However, a trend toward statistical significance (p = 0.10) was observed in the treatment group. Further research is needed to evaluate the impact of sea buckthorn-based feed supplements on insulin dysregulation in horses.
Various parts of the sea buckthorn plant are rich in bioactive compounds and nutrients, giving the plant significant medicinal potential, as supported by multiple studies in humans and animals. Processing by-products from sea buckthorn cultivation also contain many beneficial components. The effectiveness of sea buckthorn in managing insulin dysregulation has been observed in humans and rodents. In horses, insulin dysregulation has been associated with endocrine disorders such as equine metabolic syndrome and pituitary pars intermedia dysfunction, as well as systemic inflammation, some physiological factors, and inappropriate diets. Insulin dysregulation in horses can cause the development of endocrinopathic laminitis. The aim of this study was to investigate the potential of sea buckthorn processing by-products in preventing and managing the development of insulin dysregulation and metabolic syndrome in horses. To the author’s knowledge, no similar studies have previously been conducted in horses. The study was conducted with 34 horses, 18 horses in the treatment group and 16 in the control group. For six weeks the treatment group received sea buckthorn pomace granules containing seeds and the control group received granules made from hemp seed hulls. On the first, 21st and 42nd day of the study blood serum insulin concentrations were measured and a thorough clinical evaluation was done in all horses. No statistically significant (p<0.05) changes in serum insulin concentration were found in the treatment or control group. However, a trend toward statistical significance (p = 0.10) was observed in the treatment group. Further research is needed to evaluate the impact of sea buckthorn-based feed supplements on insulin dysregulation in horses.
Kirjeldus
Lõputöö
Veterinaarmeditsiini õppekaval
Märksõnad
magistritööd, insuliini düsregulatsioon, hobuste metaboolne sündroom, astelpaju, söötmine