Optimization of ultrasonic-assisted extraction conditions for polyphenols from Algerian Phlomis Crinita (Cav.) by response surface methodology
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Kuupäev
2026
Kättesaadavus
Autorid
Ajakirja pealkiri
Ajakirja ISSN
Köite pealkiri
Kirjastaja
Estonian University of Life Sciences
Abstrakt
The aim of this study is to determine the optimal conditions for ultrasonic-assisted extraction (UAE) to maximize the yield, total polyphenols content and antioxidant activity of Algerian Phlomis crinita (Cav.) extracts. The effect of extraction parameters is evaluated by response surface methodology (RSM). The antioxidant activity of the extracts is determined by the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical assay. The maximum yield obtained from ultrasound-assisted extraction is 18.54% (g per 100 g) with a total polyphenols content of 175.75 mg of Gallic acid equivalent (GAE) per gram of extract and an antioxidant activity expressed by the value of the half-maximal inhibitory concentration (IC₅₀) of 7.51 mg L-1 of Phlomis crinita extracts. The optimum conditions for this result are 60 min for extraction time, ultrasonic power of 40 W, a ratio of 1:20 g mL-1 for vegetable matter/solvent and a methanol concentration of 70% (v v-1). The results confirmed the efficiency of ultrasonic extraction and response surface methodology in optimizing the extraction of bioactive compounds from Phlomis crinita.
Kirjeldus
Received: March 31st, 2025 ; Accepted: February 4th, 2026 ; Published: February 18th, 2026 ; Correspondence: aitchaouche_feriel@univ-blida.dz
Märksõnad
Phlomis crinita (Cav.), antioxidant activity, bioactive compounds, ultrasound, optimal conditions, articles
Viide
Ait Chaouche, F. S., & Boukhari, N. (2026). Optimization of ultrasonic-assisted extraction conditions for polyphenols from Algerian Phlomis Crinita (Cav.) by response surface methodology. Estonian University of Life Sciences. https://doi.org/10.15159/AR.26.010