Sirvi Autor "Suitso, Indrek" järgi

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Bacillus smithii TBMI12 as a potential probiotic feed additive
(Eesti Maaülikool, 2014) Suitso, Indrek; Nurk, Allan (advisor); Viltrop, Arvo (advisor)
The purpose of the thesis was to investigate the potential of Bacillus smithii strain TBMI12 as a probiotic feed additive. For that safety, colonization, tolerance and challenge studies were performed with mice and pigs. Experiments showed that this strain is able to colonize gastrointestinal tract without harming the host or causing significant changes in the microbiota or disrupting the biodiversity of the gastrointestinal tract. Also colonization of the gastrointestinal tract with the Bacillus smithii TBMI12 endospores decreased the probability of Salmonella Enteritidis infection and decelerated the process of pathogenesis. Based on the results this strain has a potential to be probiotic feed additive.