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Veterinaarmeditsiini ja loomakasvatuse instituut

Selle valdkonna püsiv URIhttp://hdl.handle.net/10492/2469

Sirvi

Sirvi Veterinaarmeditsiini ja loomakasvatuse instituut Autor "Allmang, Cristin" järgi

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  • Pisipilt
    Kirje
    Evaluation of histopathology as a diagnostic method for equine sarcoids and treatment options
    (Eesti Maaülikool, 2022) Allmang, Cristin; Järveots, Tõnu (juhendaja); Kaart, Tanel (juhendaja)
    Equine sarcoids are the most common neoplasias of the skin in equines and especially relevant in horses. They present clinically as locally invasive, single or more frequently, multiple lesions with a heterogenous appearance, which highly depends on their clinical nature. Equine sarcoids are morphologically divided into 6 classes: occult, verrucous, nodular, fibroblastic, mixed, and malignant/malevolent. In diagnostics it is essential, to differentiate the sarcoids, as some forms are more resistant to therapy and have a tendency to transform into more aggressive forms. Histopathology is considered the gold-standard in diagnosis of sarcoids but the risk for aggravating the lesions when taking a biopsy is high. This study aims to evaluate if histopathology remains as the gold-standard a diagnostic tool and compare its frequency of use with other laboratory diagnostic tools like fine needle aspiration, polymerase-chain-reaction and immunohistochemistry. Additionally, the frequency of use and success rates of different treatment options in correlation with various types of sarcoids were evaluated. Data was obtained by a questionnaire that was answered by 26 equine veterinarians. 88.5% of the study population did use histopathology as a diagnostic method, most frequently for verrucous form (84.6%), mixed (76.9%), fibroblastic and nodular (53.8%). Furthermore, histology was most frequently rated “very good” (41.7%) in terms of precision and utility and none of the questioned veterinarians rated it “unreliable/ not helpful” in diagnosis of sarcoids. Fine needle aspiration was only used by 3.8%, polymerase-chain-reaction by 14.6 % and immunohistochemistry was only used by 13.3%. Surgical removal was the most frequently chosen treatment (92.3%), with a prevalence of use in nodular (61.5%) sarcoids. According to the results obtained, this study concludes that histopathology, despite the risks a biopsy poses, is still the gold-standard in diagnostics of equine sarcoids and surgical removal is the preferred treatment for these persistent neoplasias.
  • Pisipilt
    Kirje
    Terve loom : konverentsi "Terve loom 2024" posterettekanded
    (Eesti Maaülikool, 2024) Allmang, Cristin; Hussar, Piret; Järveots, Tõnu; Dūrītis, Ilmārs; Moskalenko, Lidiia; Mõtus, Kerli; Viltrop, Arvo; Teder, Siim; Karis, Priit
    Cristin Allmang, Piret Hussar, Tõnu Järveots, Ilmārs Dūrītis. SGLT1, SGLT2 and GLUT2 immunolocalization in kidneys of chicken in different age.